Jorginho missed a penalty as Italy were held to a 1-1 draw by Switzerland, leaving both sides still with a chance of automatic qualification for Qatar from Group C.
Cristiano Ronaldo scored a hat-trick as Portugal thrashed Luxembourg, while crowd trouble mars two Group I matches in World Cup Qualifying.
Northern Ireland's hopes of reaching next year's World Cup were dealt a heavy blow with a controversial first-half red card playing its part in a 2-0 loss to Switzerland.
Ian Baraclough was left "annoyed and appalled" by a controversial red card for Jamal Lewis which he felt proved decisive as Switzerland won 2-0 in Geneva.
Team news ahead of the World Cup Qualifier between Switzerland and Northern Ireland on Saturday; kick-off 7.45pm.
Bailey Peacock-Farrell's penalty save earned Northern Ireland a point as they fought out a goalless World Cup qualifying draw against Switzerland at Windsor Park.