Tammy Abraham's penalty more than nine minutes into stoppage time ended Roma’s winless run as Jose Mourinho's scraped a 1-0 victory at 10-man Spezia in Serie A.
Barcelona were held 1-1 at home by Napoli in the first leg of their Europa League knockout stage playoff tie on Thursday.
A 96th minute header from substitute Luuk De Jong saw Barcelona rescue a 2-2 draw away at city rivals Espanyol in LaLiga on Sunday.
Boubacar Kamara and Ruben Neves are two of a number of players Manchester United have been looking at in their search for a new midfielder.
La Liga champions Atletico Madrid were stunned by Granada, losing 2-1 on Wednesday, while Napoli slipped to defeat against Spezia in Serie A.