Juventus forward Paulo Dybala is to leave the club this summer as a free agent after fresh talks failed to find a resolution over his future.
Villarreal stunned Juventus with three late goals to win 3-0 in Turin (4-1 on aggregate) and reach the Champions League quarter-final.
The Champions League last 16 continues as Wednesday as Manchester City host Sporting CP and PSG take a 1-0 lead over Real Madrid to the Bernabeu.
Tammy Abraham's penalty more than nine minutes into stoppage time ended Roma’s winless run as Jose Mourinho's scraped a 1-0 victory at 10-man Spezia in Serie A.
Karim Benzema's 83rd-minute goal was enough for Real Madrid to extend their lead at the top of La Liga to nine points with a 1-0 win at Rayo Vallecano.
Dusan Vlahovic scored the second-fastest goal ever for a Champions League debutant as his Juventus side were held to a 1-1 draw at Villarreal.